Alicaforsen for the treatment of inflammatory bowel disease
V. Jairath, R. Khanna, B.G. Feagan Expert Opin Investig Drugs 2017 Jul 6:1-7……
An enema formulation of alicaforsen, an antisense inhibitor of intercellular adhesion molecule-1, in the treatment of chronic, unremitting pouchitis
P. Miner JR, M. Wedel, B. Bane & J. Bradley Aliment Pharmacol Ther (2004)…
A randomised, controlled, double blind, escalating dose study of alicaforsen enema in active ulcerative colitis
S.J.H. Van Deventer, J.A. Tami, M.K. Wedel, European Colitis Study Group Gut…
Bioavailability and therapeutic activity of alicaforsen administered as a rectal retention enema to subjects with active ulcerative colitis
P.B. Miner JR, R.S.Geary, J. Matson, E. Chuang, S. Xia, B.F. Baker & M.K.…
Safety and efficacy of two dose formulations of alicaforsen enema compared with mesalazine enema for treatment of mild-to-moderate left-sided ulcerative colitis: a randomised, double-blind, active-controlled trial.
P.B. Miner JR, M.K. Wedel, S. Xia, B.F. Baker Aliment Pharmacol Ther (2006)…
A Phase II dose ranging, double-blind, placebo-controlled study of alicaforsen enema in subjects with acute exacerbation of mild to moderate left-sided ulcerative colitis
S. J. H. Van Deventer, M.K Wedel, B.F Baker, S.Xia, E.Chuang & P.B. Miner…
Meta-analysis using individual patient data: efficacy and durability of topical alicaforsen for the treatment of active ulcerative colitis
S. Vegter, K. Tolley, T. Wilson Waterworth, H. Jones, S. Jones, D. Jewell…
Alicaforsen retention enema induces long-term remission in patients with ulcerative colitis
Heetun Z, Gibson D, Keegan D, Byrne K, Mulcahy HE, Cullen G, Doherty G Irish…